SCOPE OF NANOMEDICINES AGAINST CORONARY ARTERY DISEASE: A REVIEW
Monawara Begum* and H. K. Sharma
ABSTRACT
Coronary artery disease (CAD) is a very composite chronic heart disease which leading to cause of death and impairment global.CAD is mainly happened due to genetic and environmental factors, the effects of which are mainly interceded through cardiovascular risk factor.CAD is generally associated when the major blood vessels which supply blood,oxygen and other nutrient to heart become damaged. Cholesterol containing plaque in arteries and inflammation are also the main reason for CAD. Healthy arteries have some elastic fibers that are like rubber bands in the tissue that are allow to expansion and recoil during blood flow, In most of the cardiovascular diseases, elastic fibers in arteries get damaged, which creating hooks that can be used to target drugs. Surgical treatment is one of the oldest method of management of these diseases. But these techniques can lead to additional morbidity in that they provoke central nervous system disturbances, as well as gastrointestinal complications in few patients.The application of nanoscience in relation to heart diseases which provides some technology to design and develop newer cardiac instruments, which are not only smaller in size but also more effective, the nanoparticles, coated with a sticky protein, which attached onto damaged arteries and can deliver a drug to the site in slow release mood and can deliver an array of drugs to the damaged or clogged artery. The main aim of this review is to provide a general overview of the potential benefits of nanotechnology in coronary artery disease..
Keywords: Coronary artery disease,management of CAD, nanomedicine,
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