EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-3 IN HYPOXIA-INDUCED VASCULAR DEVELOPMENT: A REVIEW

Obeagu, Emmanuel Ifeanyi*, Okoroiwu,I.L., Ijioma, Solomon Nnah, Daniel-Igwe,Gloria

ABSTRACT

Vascular development is controlled by two processes: vasculogenesis and angiogenesis.Vascular development is regulated by various growth factors especially the vascular endothelial growth factor (VEGF). Hypoxia stimulates vascular development.The most important cellular response to hypoxia is transcriptional activation of a number of genes.The protein products of thes genes,of which VEGF-A is one of the best characterised,regulate metabolic adaptation and cell survival as improve oxygenation through erythropoiesis and neovascularisation

Keywords: Hypoxia, Vascular Endothelia Growth Factor (VEGF), Vascular Development.

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