EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , 

 ISSN 2394- 3211

Impact Factor: 4.161

 ICV - 79.57

Abstract

WHO AFRO TRANSFORMATION AGENDA AT WORK: A TEST CASE IN THE INVESTIGATION OF A SUSPECTED CASE OF EBOLA VIRUS DISEASE THAT TURNED OUT NEGATIVE.

Murebwa Chirambo Rufaro*, Muzala Kapina, Elizabeth Chizema, Mazaba-Liwewe Mazyanga; Ndumba Idah, Musumali Mbaulo, Mweemba Nora, Asaph Choonga, Harison Ng’uni, Herbert Mbewe, Ngonda Saasa, Katendi Changula, Qiu Yongjin, Kajihara Masahiro, Akina Mori, Yasuko Orba, Edgar Simulundu, Ladslav Moonga, Kashihara Sakae, Ayato Takada, Aaron S. Mweene and Mufunda Jacob

ABSTRACT

Background: Ebola virus disease (EVD) was first reported in the African region in DRC and Sudan in 1976. In the recent past (2014), an outbreak was reported in Guinea, which mostly affected West African countries, but with the greatest impact on Liberia and Sierra Leonne, where many cases and deaths have been recorded. The lessons learnt from this outbreak in terms of the rate at which cases were confirmed and the response among other issues led the incoming World Health Organization (WHO) Regional Director for Africa to come up with the concept of Transformation Agenda, which basically focusses on the need to change the way WHO does its business. Objective: To document the investigation of a suspected EVD case within the principles of the Transformation Agenda. Methodology: A recently EVD trained health worker suspected a 30 year old man of Ebola, who presented at the health center with epistaxis, hematemesis and fever. There was no history of having traveled to DRC or any EVD affected countries and no contact with suspected or confirmed EVD case. The patient was immediately quarantined, together with immediate family members and the district, province and national levels notified accordingly. Meetings were convened for a rapid and transparent response and a Rapid Response team was dispatched to the health center which is 154km from Solwezi and 2km from the DRC border. He was commenced on IV fluids and magnesium triscillicate. A blood sample was collected and taken to the University of Zambia Veterinary laboratory in Lusaka. Daily feedbacks were sent to WCO and MoH headquarters. Results: The patient’s plasma was tested for Ebola, Marburg and Filovirus genes using Polymerase Chain Reaction (PCR) techniques (Protocol for Ebola Diagnosis at UNZA-VET, YEAR). The samples were handled in a BSL-3 containment laboratory. The results were Negative - No amplification of Ebola, Marburg or Filovirus genes. Conclusion: It took less than 3 days to isolate the case, collect the sample and confirm the diagnosis from the initial notification of the case. This was possible because of the implementation of the tenets of the transformation agenda (accountability, responsiveness, transparency, tolerance to non-compliance), including the team work between WHO, MoH and the Veterinary Laboratory and readily available resources to respond.

Keywords: magnesium triscillicate, Filovirus genes, Solwezi.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 November 2017 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

  • EJPMR NOVEMBER ISSUE PUBLISHED

    NOVEMBER 2017 Issue has been successfully launched on 1 November 2017

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from 3.628 to 4.161 due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 45.77, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process)