EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , 

 ISSN 2394- 3211

Impact Factor: 4.161

 ICV - 79.57

Abstract

ANTIBACTERIAL AND ANTIBIOFILM ACTIVITIES OF PEPPERMINT (MENTHA PIPERITA LINN) AND MENTHOL MINT (MENTHA ARVENSIS LINN) ESSENTIAL OILS ON AGGREGATIBACTER ACTINOMYCETEMCOMITANS ISOLATED FROM ORODENTAL INFECTIONS.

Ramanath Karicheri and Beena Antony*

ABSTRACT

Introduction: Aggregatibacter actinomycetemcomitans is one of the key pathogen associated with periodontal diseases as well as systemic infections. Giving importance to the higher incidence rate of periodontitis and resistance among oral bacteria to antibiotics, there is a need for alternate treatment regimen especially from natural resources. The main objective of the present study was to elucidate antibacterial and antibiofilm potential of the essential oils of Mentha piperita Linn and Mentha arvensis Linn against A.actinomycetemcomitans isolated from patients with orodental infections. Methodology: Essential oils of Mentha piperita Linn and Mentha arvensis Linn leaves were distilled in Clevenger’s apparatus by Neo-Clevenger’s method. Antimicrobial action was determined by disc diffusion method. Minimum inhibitory concentration (MIC) was determined by microbroth dilution technique. Tissue culture plate method was employed for demonstration of antibiofilm activity. Results: 77.9% and 76.5% of the isolates showed antibacterial activity against Mentha piperita Linn and Mentha arvensis Linn essential oils respectively by disc diffusion methods. The MIC ranged between 3.125μl/ml to 12.5μl/ml. The minimum biofilm inhibition concentration (BIC50) was achieved at 100l/ml concentration for both the essential oils Conclusion: Essential oils of M.piperita and M.arvensis showed good antibacterial as well as antibiofilm activity at low concentrations and can be considered as an alternate treatment option for the control of periodontitis by A.actinomycetemcomitans.

Keywords: Aggregatibacter actinomycetemcomitans, Mentha piperita, Mentha arvensis, Minimum inhibitory concentration (MIC), biofilm inhibition concentration (BIC50).


[Full Text Article]

INDEXING

NEWS & UPDATION

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 November 2017 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

  • EJPMR NOVEMBER ISSUE PUBLISHED

    NOVEMBER 2017 Issue has been successfully launched on 1 November 2017

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from 3.628 to 4.161 due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 45.77, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process)