EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

IN VITRO ANTI OXIDANT ACTIVITY OF ETHANOLIC EXTRACT OF DIOSPYROS PANICULATA Dalz, BARK

Mithun K. Sebastian* and Shan P. Mohammed

ABSTRACT

Diospyros Paniculata is a tree which belongs to the family Ebanacea which has been used as a folkforic medicine in ayurveda and siddha. It has been commonly used in the treatment of ulcer, burns, poisoning etc. Here the study was conducted to evaluate the In vitro Anti oxidant activity of bark extract of diospyros paniculata by DPPH, Hydroxyl radical scavenging methods. The effect of the extract is assessed by the ability to scavenge DPPH radicals and Hydroxyl radicals. The results obtained indicate that the Ethanolic extract of Diospyros Paniculata (EEDP) has significant In vitro Anti oxidant activity (P<0.001).The IC 50 value of EEDP by DPPH method was found to be 100μg/ml as compared to standard which is 70μg/ml and Percentage Inhibition of Hydroxyl radical at dose 1000μg/μl of EEDP is 38.07% as that of standard which is 75.44%.

Keywords: Diospyros Paniculata, In vitro, Anti oxidant, DPPH, Hydroxyl radical scavenging.

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