EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

WOUND HEALING ACTIVITY OF METHANOLIC EXTRACT OF THE PEEL OF ABELMOSCHUS ESCULENTS

P. Senthil Kumaran*, A. Sumathi, K. R. Shanthini and J. Mallika

ABSTRACT

The history of medicine is as that old as human civilization. Nature is provided a complete storehouse of remedies to cure all ailments of mankind. Among the biotic and abiotic elements of nature, they plants are indispensable to man as they provide food, clothing and shelter the three important necessities of life along with other useful product us medicines to alleviate his suffering from injury and disease. The preliminary phytochemical analysis was carried out in the methanol extracts. It was found that glycosides, Carbohydrate, amino acids and tannins. The methanol extract was screened for wound healing activity by excision and incision wound model, in the form of an ointment having 2 concentrations (10%and 20 % w/w) of peel extract in simple ointment base. Both the concentrations of the methanol extract showed significant response in both the wound types tested when compared with the control group. Povidine ointment (0.2%w/w) was used as an standard drug. The extract having significant (p>0.05 and p<0.01) wound healing activity compared to control. On the basis of the results obtained suggest marked that extracts have significant wound healing activity of Abelmoschus esculents. The results supported the traditional use of this plant in some painful and wound healing conditions.

Keywords: Abelmoschus esculents, Phytochemical screening, wound healing.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia