EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

EVALUATION OF ANTIMICROBIAL ACTIVITY OF THE AQUEOUS AND CHLOROFORM EXTRACTS OF LEAVES OF COUROUPITA GUIANENSIS BY WELL DIFFUSION METHOD

Praveen Kumar Uppala*, Dr. K. Atchuta Kumar, D. J. Vinay Ramji and Uma Shankar Gorla

ABSTRACT

Objective: To investigate Antimicrobial activity (Antibacterial, Antifungal) of the Aqueous and Chloroform Extracts of Leaves of Couroupita guianensis by Well Diffusion Method. Methods: The Antimicrobial activity (Antibacterial, Antifungal) of the Aqueous and Chloroform Extracts of Leaves of Couroupita guianensis by Well Diffusion Method and the results were compared for the both extracts. Antibacterial activity is compared with standard antibiotic Penicillin (10mg/ml) and antifungal activity is compared with standard antibiotic Clotrimazole (10mg/ml). Results: The chloroform extract of Couroupita guianensis showed better activity against the fungus like Candida albicans with the zone of 4.36±0.84 followed by Aspergillus niger with zone of diameter 2.3127±0.668 and the aqueous extract shows better activity against the bacteria like, Staphylococcus aureus zone of diameter is 2.2 Escherichia coli the zone of diameter 2.67. In the present study, both in bacteria and fungi chloroform and aqueous extracts showed a varying degree of inhibition of the growth against tested organism. Conclusion: From the above finding concluding that, this study evaluated the inherent antifungal activity of chloroform as well as the antifungal activity of aqueous extract of couroupita guianensis. From the obtained results it can be concluded that although chloroform itself has antifungal activity, chloroform extract of couroupita guianensis has a synergistic activity.

Keywords: Couroupita guianensis, Candida albicans, Aspergillus niger, Staphylococcus aureus, Escherichia coli.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia