EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

PERIPHERAL RETINAL NERVE FIBRE LAYER (RNFL) THICKNESS AND ITS CORRELATION WITH HIGH MYOPIA: A NOVEL EXCLUSIVE NORMOGRAM

Abdul Waris*, Adil Asghar, Mousami Malakar, Humayun Asharf, Syed Nasir Askari, Anupam Ahuja and Syed Mobashir Yunus

ABSTRACT

Purpose: To evaluate the association of high myopia with retinal nerve fibre layer (RNFL) thickness specially in the peripheral retina after ruling out other causes of RNFL thinning. METHODS: Fifty highly myopic eyes and forty emmetropic eyes of patients was selected after excluding concomitant ophthalmic disorder and RNFL thickness measured using the Fourier domain optical coherence tomography (FD OCT). RESULTS: The overall mean RNFL thickness in the myopic groups and control were 87.89 μm and 111.64 μm respectively. The mean retinal nerve fibre thickness was significantly less in myopic eyes as compared to control group (p =0.0000). Mean loss of retinal thickness at periphery was 21.22±9.27 % and it strongly correlated with spherical error (r2=0.20). CONCLUSIONS: Retinal nerve fibre thickness was significantly decreased in myopic eyes as compared to emmetropic eyes. The peripheral retinal & RNFL of periphery are more stretched and affected in high myopia. Hence, if we focus on the RNFL of periphery after ruling out other disorder specially open angle glaucoma we get an exclusive correlation of RNFL thickness and high myopia which avoid wrong interpretation.

Keywords: RNFL (retinal nerve fibre layer), OCT (optical coherence tomography), Myopia, Normogram.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia