EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

FT-IR ANALYSIS AND IN VITRO ANTIBACTERIAL ACTIVITY OF PROSOPIS JULIFLORA

Nagalakshmi G. and Anuradha R*.

ABSTRACT

Prosopis juliflora, an Indian Mallow has been used in the treatment of various diseases in different parts of the world since time immemorial. The present investigation was carried out to find the effect of methanolic extracts of flowers of Prosopis juliflora through FT-IR Spectroscopy method and its antibacterial activity. The FT-IR analysis confirmed the presence of phenol, alcohols, alkanes, carboxylic acids, ketones, alkenes, aromatics, ethers, and aliphatic amines compounds, which showed major peaks. The anti bacterial activity of the methanolic extracts of Prosopis juliflora (25,50,75,100, 200,300mg/ml) was also tested against two human pathogenic bacteria such as Escherichia coli and Staphylococcus aureus. The anti bacterial potent of the extracts was found to be dose dependent. The phytochemical analysis of the plant was carried out. The results revealed the quantitative analysis of following classes of natural constituents: flavonoids, alkaloids, saponins, phenols and tannins in the range of (25%), (15%), (10%), (22%) and (18%), respectively. The crude fiber and ash content were also analyzed and found as (12%) and (7%), respectively whereas, pectic substances were calculated as (12%). The activity of the flower of Prosopis juliflora was due to the presence of various secondary metabolites. Hence the plant can be used to discover bioactive natural products that may serve as leads in the development of new pharmaceuticals research activities.

Keywords: Prosopis juliflora, FT-IR analysis, in vitro antibacterial activity.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia