ANTIOXIDANT ACTIVITY OF CARPESIUMROSEULATUMON THE ETHANOL EXTRACTION

In Sook Kye MD, PhD, *Man Kyu Huh MD, PhD

ABSTRACT

The objectives of this study were to determine antioxidant activities and reducing power activity of ethanol extracts of Carpesium roseulatum (Composite) leaves, stems, and roots. The antioxidant activity of the C. roseulatum extracts was measured on the basis of the scavenging activity of the hydroxyl radical (-OH), 1, 1- diphenyl 2-picrylhyorazyl (DPPH), and ferric reducing antioxidant power (FRAP). These results show that C. roseulatum has some phytochemical constituents which may be active against the free radicals (OH and DPPH) and reducing power activity. OH scavenging activity of C. roseulatum was evaluated at 22.2-31.1 µg/ml at 0.1 mg/ml and the highest as found to be 67.4% at 8.0 mg/ml. DPPH scavenging activity of C. roseulatum was evaluated at 17.9-45.1 µg/ml at 0.1 mg/ml and the highest as found to be 71.1% at 8.0 mg/ml. Reducing power activity of C. roseulatum was evaluated at 26.8-38.1 µg/ml at 0.1 mg/ml and the highest as found to be 64.2% at 8.0 mg/ml.

Keywords: Antioxidant activities, hydroxyl radical (OH), 1, 1- diphenyl 2-picrylhyorazyl (DPPH), ferric reducing antioxidant power (FRAP), Carpesium roseulatum.