EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

GLC STUDY AND BIOLOGICAL ACTIVITIES OF THE VOLATILE OIL COMPONENTS OF SOME IN VIVO AND IN VITRO TISSUES OF FOENICULUM VULGARE MILL. VAR. VULGARE

Rehab H. Abd-Allah*, Ehsan M. Abo Zeid, Mahmoud M. Zakaria and Samih I. Eldahmy

ABSTRACT

Foeniculum vulgare Mill. is a wild, annual herb native to the Mediterranean area. The plant is commonly known as the bitter fennel or the common fennel, known in Egypt as "shamar".[1] This plant is rich in important pharmacologically active secondary metabolites as volatile oils, resins, coumarins, terpenes, sesquiterpenes, triterpenoid, saponins and acetylenic compounds; while alkaloids are.[2] This study focused on comparing the volatile oil constituents of different plant parts of wild, cultivated plant as well as in vitro induced calluses and plantlets using gas chromatography-mass spectroscopy (GLC/MS). Also, biological study of the plant volatile oils was performed to screen different activities like analgesic, anti-inflammatory, antipyretic, antispasmodic and anxiolytic activities which were highly significant. Moreover, a comparative antimicrobial study was conducted to extracts of both the wild plant and the micro-propagated plants. The observations were highly valuable as extracts of the micro-propagated plants showed stronger activity than the extracts of the wild plant against the tested microorganisms and also showed activity against Candida albicans contrary from the wild plant extracts that showed no activity against it.

Keywords: Foeniculum vulgare, Volatile oils, Callus, In vitro propagation, GLC-MS of extracts, Biological activity.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia