EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , 

 ISSN 2394- 3211

Impact Factor: 4.161

 ICV - 45.77

Abstract

EFFECT OF FIRST TRIMESTER PREGNANCY ON TRIIODOTHYRONINE, THYROXINE AND THYROID STIMULATING HORMONE AT VARIOUS AGE INTERVALS IN WOMEN OF PORT HARCOURT METROPOLIS, NIGERIA

*Ben-Chioma A., Elekima I. and Nwachuku, E. O.

ABSTRACT

The effect of first trimester gestation on Triiodothyronine (T3), Thyroxine (T4) and Thyroid stimulating hormone (TSH) were assessed in 90 female subjects between the ages of 18-45 years. The test subjects all in their first trimester pregnancy were 60 and the non-pregnant (control) subjects excluded by serum pregnancy test were 30. Age interval of 18-26, 27-35 and 36-45 years were considered for both the test and control subjects. Samples obtained from these subjects were analyzed using the enzyme immunoassay method and statistical analysis carried out using Graphpad prism 5.2. When control was compared to pregnant subject, T4 and TSH showed significant increase and decrease respectively while T3 indicated no significant difference. When age intervals were considered, pregnant women of 18 -26 years showed significant increases and decreases in T3, T4 and TSH respectively. In 27-35 years, significant increase and decrease were seen in T4 and TSH respectively while in 36-45 years, significant decrease was seen in TSH. These significant changes in the activities of the hormones in the early period of gestation indicate great demand fo r the hormones by the mother and for the sustenance of the growing child during pregnancy.

Keywords: Pregnancy, T3, T4, TSH, First trimester.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process)