A STUDY OF PRESCRIBING PATTERNS OF ANTIBIOTICS FOR SURGICAL PROPHYLAXIS IN TERTIARY CARE TEACHING HOSPITAL

*Nabeel Abdul Rasheed, Karthikeyan V., Ajisha, Parvathy Rajeev, Akash Simon and Abdul Jaleel

ABSTRACT

Objective: The objective of the study was to audit the prescribing pattern of surgical antibiotic prophylaxis in departments of general surgery, orthopaedics. Methods: A prospective observational study was conducted over a 6 months period in a tertiary care teaching hospital. The main outcome measure of the study was the use and administration of prophylactic antibiotics for surgeries. Results: A total of 110 patients were collected during study period. Out of the patients for whom prophylaxis was recommended and was given, cephalosporins (56.9%) and Aminoglycosides (18.9%) were prescribed the most. The most common surgery carried out was cortical mastoidectomy, hernioplasty, appendectomy followed by orthopedics procedures. Ceftriaxone, cefuroxime and cefotaxime was the most commonly used cephalosporins. Conclusion: Aminoglycosides (Amikacin and Gentamycin), Nitro Imidazoles (Metronidazole) and Fluoroquinolones (Ciprofloxacin and Ofloxacin) are the most used anti-microbial for prophylactic therapy following Cephalosporins.

Keywords: Prescribing pattern, Surgical prophylaxis, Antibiotics.