EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , 

 ISSN 2394- 3211

Impact Factor: 4.161

 ICV - 45.77

Abstract

EVALUATION OF LIPIDS AND LIPOPROTEIN LEVELS OF PREMENOPAUSAL AND POST MENOPAUSAL WOMEN IN PORT HARCOURT METROPOLIS

Ebirien-Agana Samuel Bartimaeus* and Stella Urekweru Ken-Ezihuo

ABSTRACT

Background: Menopause is regarded as one of the risk factors for cardiovascular diseases. Objective: This study was designed to estimate the serum levels of total cholesterol, triglycerides, high density lipoprotein cholesterol, low density lipoprotein cholesterol, very low density lipoprotein cholesterol and atherogenic index of plasma and Castelli risk index 1 and 11 and the effect of body mass index (BMI) and blood pressure (BP) in pre-menopausal and post-menopausal women in Port Harcourt metropolis. Methodology: The lipoproteins, blood pressures and BMI were determined using standard procedures. Results: The mean age of the pre-menopausal women was significantly different (p<0.05) from that of the post-menopausal women. Significant increase (p<0.05) in means of the lipoproteins between the two groups of women was found in TC, HDL-C and LDL-C. Remarkable increase in the systolic and diastolic blood pressure of the post-menopausal women up to 40% (hypertensive) above the normal range was observed. Higher percentage of the post-menopausal women were over weight and obese. The AIP and CRI (I and II) ratios between the two groups were seen to be higher in the post-menopausal women. Conclusion: The present study shows that dyslipidaemia, blood pressure and body mass index are significantly associated with menopausal transition. The lipid profile of the post-menopausal women in this study is very unfriendly. Thus, it is proposed that lipoprotein ratios and triglyceride based index (atherogenic index of plasma; AIP) should be routinely done in post-menopausal women since they can add significant diagnostic value when assessing the cardiovascular risk of menopausal women.

Keywords: Lipoprotein, Pre-menopausal, Post-menopausal, Cardiovascular disease, Atherogenic Index of Plasma, Castelli Risk Index.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process)