EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

A PROSPECTIVE STUDY ON MEDICATION ADHERENCE AMONG PATIENTS WITH TYPE 2 DIABETES MELLITUS IN SOUTH INDIAN TERTIARY CARE HOSPITAL

Roshin Elizabeth Mathew, Aswathy Vijayan, Mamen Alex, Veena Vijayan G.* and Dr. Archana Babu

ABSTRACT

Aim: The main objective of the study was to evaluate Medication Adherence and also to find its association with Severity of Depression in Type 2 Diabetes Mellitus patients. Materials and Methods: A prospective-observational study carried out among 200 patients with Type II Diabetes Mellitus in the General Medicine Department for a period of six months based on inclusion and exclusion criteria. A structured interview with patient or parent was conducted by using various questionnaires to elicit information about severity of depression by Hamilton Depression Rating scale(HAM-D) and medication adherence using Morisky Medication Adherence Scale-8(MMAS-8). Then data were well analyzed. Finally, correlation between Medication Adherence and Severity of Depression were assessed. Result: Majority of them shows (57%) high adherence, followed by medium adherence only 14.5% show low adherence. About 27.6% of poor adherence to anti-diabetic medication is due to forgetfulness, lack of disease knowledge, Long treatment duration, Increased cost of therapy, lack of family or social support, Polypharmacy, only 6.5% due to side effects of medicine especially for patients on insulin. Diabetics without depression are highly adherent to medication (49.1%) medium adherence (28.1%), only 13.8% shows low adherence. Majority of diabetic patients with severe/very severe depression shows low adherence to medication (44.8%), followed by medium adherence (28.1%) and only 9.6% are highly adherent. Conclusion: The studies on medication adherence will definitely help the physician to improve the prescribing pattern, efficient clinical management delays the progression of disease, reduce the diabetic related complications, improves the quality of life, improves clinical outcomes of patients and better QOL of patients.

Keywords: Diabetes Mellitus, Depression, Medication Adherence, MMAS-8, HAM-D.

[Full Text Article] [Download Certificate]