EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , 

 ISSN 2394- 3211

Impact Factor: 4.161

 ICV - 79.57

Abstract

EXPOSURE TO UPPERCOTT AFFECTS HEMATOLOGICAL INDICES IN MALE ALBINO WISTAR RATS

Modo Emmanuel U.*, Uboh Friday E., Agiang Margaret A., Dongo Bright S., Etim Gabriel O. and Wopara Iheanyichukwu

ABSTRACT

The hematological indices of Albino rats treated with uppercott at 2.5%, 5% and 7.5% of LD50 were assessed. Forty-five male albino rats, divided into 5 groups of nine rats each were used. Group 1 (control) was fed rat chow only; group 2 was used as the vehicle (Control administered only oil); while groups 3-5 (experimental groups) were treated with uppercott at different concentrations. The results as compared to the control groups showed that WBC concentration was significantly higher (p<0.05) in 5%M compared to OCM and other test groups. RBCs were not significantly decreased across all test groups. HGB was slightly decreased in 7.5% M compared to all controls and test groups, while HCT significantly increased in 5%M. No significant difference was observed in the MCV concentration, whereas, MCH and MCHC significantly decreased (p<0.05) in 7.5%M compared to all controls and test groups. Platelets concentration significantly (p<0.05) increased in OCM compared to NCM and other test groups. Lymphocytes decreased significantly (p<0.05) in 7.5%M compared to control and other test groups. Over all data showed that uppercott had a deliterous effect on hematological indices suggesting that uppercott is an environmental pollutant, which should be used with caution.

Keywords: hematology, uppercott, vehicle, environment, olive oil.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process)