EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , 

 ISSN 2394- 3211

Impact Factor: 4.161

 ICV - 79.57

Abstract

ANTIBACTERIAL ACTIVITY OF ETHANOLIC ROOT EXTRACTS OF UVARIA CHARMAE ON STAPHYLOCOCCUS AUREUS

Inyang Imeobong J., Fischer Victor, Eyo Aniekan-Augusta O.* and Udonkang Mfoniso I.

ABSTRACT

Many different medicinal plants have been utilized in the treatment of infections caused by Staphylococcus aureus due to the increased antibiotic resistance exhibited by this organism. One of such medicinal plants is Uvaria charmae, a small wild shrub found in the south, east and northern parts of Nigeria. This plant has been incorporated into many herbal preparations sold under different proprietary names in Nigeria, with claims of antibacterial activity particularly against S. aureus. This study was carried out to determine the antibacterial activity of Uvaria charmae ethanolic root extract on S. aureus. The results of antibacterial susceptibility testing indicated that Uvaria charmae root extracts had no antibacterial effect on S. aureus at concentrations of 25mg/dl, 50mg/dl, 100mg/dl and 200mg/dl compared with standard commercial discs of Ciprofloxacin and Levofloxacin at similar concentrations which showed zones of inhibition >21mm depicting susceptibility. This study suggests that Uvaria charmae does not have antibacterial effect against S. aureus and is thus unsafe for continuous usage for this purpose as this could prove toxic. Public awareness on the effects of indiscriminate use of herbal medicines for treatment of bacterial infections should be encouraged. Government regulation should be intensified through its regulatory agencies in the verification of claims by alternative medicine practitioners before permitting sale of herbal products.

Keywords: Antibacterial activity, Uvaria charmae, Staphylococcus aureus.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process)