EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , 

 ISSN 2394- 3211

Impact Factor: 4.161

 ICV - 45.77

Abstract

EVALUATION OF METABOLIC COMPOUNDS OF CATHARANTHUS ROSEUS AND ITS ANTICANCER ACTIVITY

Susmitha Sudevan, Ranganayaki Paramasivam, Shalini Sundar, Awathy A. R, Rincy R. and Dr. Vijayaraghavan Ramasamy*

ABSTRACT

The aqueous and methanol extract of Catharanthus roseus (leaves) was accessed for their antimicrobial activity. The Antimicrobial activity was performed against pathogens such as Salmonella, Klebsiella, Proteus, E.coli and Shigella. The phytochemical analysis showed the presence of flavonoids, Saponins, Alkaloids, Amino acids, Tanins and Terpenoids in both aqueous and ethanol extracts. The active components present in the extract are found to be amino acids, Alkaloids, Lipids and terpanoids. The antimicrobial activity of active components present in the leaf extract shows inhibition of Salmonella and Klebsiella. Catharanthus roseus exhibit anticancer activity in in-vitro in Breast cancer cell line (MCF-7) and it was found effective. The inhibitory concentration found at 18.67μg/ml. The research work which is going on this direction is a proof of benefits by reducing toxicity of chemo and radio therapies and providing better and healthier life style by Catharanthus roseus.

Keywords: Catharanthus roseus, Terpenoids and MCF-7.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • EJPMR SEPTEMBER ISSUE PUBLISHED

    SEPTEMBER 2017 Issue has been successfully launched on 1 September 2017

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 September 2017 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from 3.628 to 4.161 due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 45.77, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process)