EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , 

 ISSN 2394- 3211

Impact Factor: 4.161

 ICV - 45.77

Abstract

“COST-EFFECTIVENESS ANALYSIS OF CONGENITAL HYPOTHYROIDISM IN NEONATES BORN IN UTTAR PRADESH: A PILOT STUDY”

*Tiwari Vandana Ph. D, Husain Nuzhat MD, Awasthi P Namrata MD and Pandey M. Chinta Ph. D.

ABSTRACT

Congenital hypothyroidism (CH) has long been recognized as a cause of mental retardation. Untreated, CH has devastating effects on growth and development of infants. Therefore present study was aimed to determine the incidence of hypothyroidism in neonates in our population and to determine whether a new-born screening for CH is cost-beneficial from a societal perspective. Heel puncture blood was obtained from neonates born in department of Obstetrics & Gynaecology at RMLCH after 48 hours of birth for screening of CH. Family history of thyroid disease, and other obstetric and relevant family history was recorded for each neonate. A commercial TSH assay was done for detection and specimens with TSH concentrations >20mIU/L were considered to suggest CH and additional follow-up testing was pursued. Incidence was estimated, costs for the detection and treatment of abnormality was compared to the projected benefits of preventing the mental retardation and consequent productivity losses. Out of 1210 neonates screened three were found positive for Congenital Hypothyroidism. Mother of two of these neonates was suffering from hypothyroidism and one was normal. The prevalence of Congenital Hypothyroidism in our study was 3/1,210 (approximately one per 400 live births during the period of study). Detection of CH with timely testing in neonates confirms the diagnosis and allows early treatment within a time frame that prevents mental retardation and maximizes a positive health outcome and quality of life.

Keywords: Congenital Hypothyroidism (CH); Thyroid Stimulating Hormone (TSH); Disability Adjusted Life Years (DALYs).


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process)