EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , 

 ISSN 2394- 3211

Impact Factor: 4.161

 ICV - 45.77

Abstract

SCREENING OF TURBINARIA FOR THE PRESENCE AND STABILITY OF ANTIMICROBIAL COMPOUNDS

Bany Joy* and Manju Kuruvilla

ABSTRACT

Seaweed of Phaeophyceae namely, Turbinaria sp was collected from the South Eastern Coast of Tamilnadu (Rameshwaram). The extracts were subjected to antimicrobial assay by agar well diffusion method. Clinical isolates of two gram positive (Staphylococcus sp, Bacillus sp), five gram negative (Proteus sp, Pseudomonas sp, Klebsiella sp, E.coli, and Salmonella sp) and one fungal strain Candida albicans) were used for the antimicrobial assay. Large inhibitory zone against Staphylococcus sp, Bacillus sp, Proteus sp, Klebsiella sp and E.coli was formed by ethanol, chloroform and ethyl acetate extracts of Turbinaria sp was and ethanol extracts of Turbinaria sp showed a good inhibitory zone against Candida albicans. Thin layer chromatography analysis for all extracts were performed for better resolution of the compounds using methanol-chloroform (1:1). Silica gel column chromatography of the chloroform and ethanol extracts of Turbinaria sp was done for partial purification of antimicrobial compounds since these compounds have better antimicrobial activity. The different fractions obtained from column chromatography were tested for antimicrobial activity. Fractions 2-11 of ethanol extract and 1-11 of chloroform extract of Turbinaria sp was active against various isolates. Stability of the antimicrobial compounds was tested for a period of one and a half months and was found to be better in its activity upon storage also.

Keywords: Phaeophyceae, antimicrobial, Turbinaria.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process)