EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394- 3211

Impact Factor: 4.161

 ICV - 79.57

Abstract

ANTIMICROBIAL ACTIVITY, PHYTOCHEMICAL SCREENING AND GC-MS ANALYSIS OF PETROLEUM ETHER EXTRACT OF THE MEDICINAL PLANT CYATHEA NILGIRENSIS HOLTTUM

*G. Pradheesh, J. Suresh2, S. Suresh, V. Alexramani and S. I. Hong

ABSTRACT

The present study was carried out to identify the bioactive compounds present in the Pet-ether extract of Cyathea nilgirensis Holttum and to study the antimicrobial activity of the petroleum ether extract of the plant. The zone of inhibition and percentage of inhibition of the extract against test microorganisms was determined using disc diffusion method. The test microorganisms included six standard bacterial species - Staphylococcus aureus, Bacillus subtilis, Micrococcus luteus, Escherichia coli, Salmonella paratyphi and Klebsiella pneumoniae and two fungal species - Candida albicans and Aspergillus niger. The primary and secondary metabolites were identified using spot tests. Various bioactive compounds were identified using GC-MS analysis. The petroleum ether fraction inhibited the chosen microbial species. GC-MS analaysis had shown the presense of compounds like Squalene, Pentacosane, Triacontane, 5,10 –dimethy- l6,8- bisdehydro pentapentadecafulvalene and 4-[10-(3,4-Dimethoxy) phenanthryl] morpholine in the petroleum ether extract.

Keywords: Cyathea nilgirensis Holttum, Pet-Ether Extract, Preliminary screening, GC-MS Analysis & Antimicrobial Activity.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process)