EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , 

 ISSN 2394- 3211

Impact Factor: 4.161

 ICV - 79.57

Abstract

EVALUATION OF THE EFFICACY OF PANAX GINSENG SUPPLEMENT ON NICOTINE AND CHRONIC STRESS INDUCED REPRODUCTIVE TOXICITY IN MALE ALBINO WISTAR RATS

Ukoh Imoh Emmanuel*, Bisong Sunday Agba and Ebong Patrick Ekong

ABSTRACT

The current study assessed the efficacy of panax ginseng supplement in nicotine and stress induced reproductive toxicity in 48 male albino Wistars rats (150-200g body weight). The rats were grouped into two sets, the first set was control, stress, nicotine and nicotine + stress induced, while the second sets were treated with panax ginseng. The result was analysed using One way ANOVA, followed by post hoc multiple comparisons and level of significance set at p<0.05. Sperm count, motility, rapid progressive forward movement and sperm viability were significantly reduced (p<0.05) in nicotine + stress compared to stress and nicotine groups. Percentage of sperm debris, non-motile sperm and slow progressive forward movement were significantly increased (p<0.05) in nicotine + stress compared to stress and nicotine groups. Luteinizing hormone and testosterone levels were significantly reduced (p<0.05) in nicotine + stress compared to stress and nicotine. Follicle stimulating hormone levels were significantly reduced (p<0.05) in stress and stress + nicotine, but significantly increased (p<0.05) in nicotine compared to control. Testicular and epididymal tissues of nicotine + stress rats were seriously impaired compared to stress and nicotine rats. Panax ginseng significantly (p<0.05) recovered the changes in the assessed sperm characteristics and hormonal parameters, and as well improved the testicular and epididymal tissue alterations observed in the untreated groups. Panax ginseng appeared to ameliorate the adverse effect induced by nicotine plus chronic stress on male reproductive parameters.

Keywords: Testicular and epididymal tissues, sperm debris, nicotine + stress.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 December 2017 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • EJPMR DECEMBER ISSUE PUBLISHED

    DECEMBER 2017 Issue has been successfully launched on 1 December 2017

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from 3.628 to 4.161 due to high quality Publication at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process)