COMPARING THE EFFICACY AND TOLERABILITY OF CARBAMAZEPINE AND OXCARBAZEPINE AS A MONOTHERAPY OF TRIGEMINAL NEURALGIA
Abdulrahman M. Alahdal*
Introduction: The objective of this review was to explore available clinical trials comparing the efficacy and tolerability of CBZ and OXC. The keywords and search strategy demonstrated by the summary of search results. The flow of the information through the different stages of the systematic review (identification, screening, eligibility, inclusion) was demonstrated. An electronic search was conducted on Medline, PubMed, Cochrane library and Science Direct databases. The bibliographies of retrieved papers were screened for more articles that are relevant. Conclusion: The findings of this review showed better efficacy and tolerability of OXC than CBZ in the treatment of trigeminal neuralgia. However, additional robust randomized clinical trials are strongly recommended to yield stronger evidence for the superiority of OXC in the management of trigeminal neuralgia compared to CBZ.
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