EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , 

 ISSN 2394- 3211

Impact Factor: 4.161

 ICV - 79.57

Abstract

EVALUATION OF ANTI-HYPERLIPIDEMIC ACTIVITY OF BOUGAINVILLEA GLABRA “SNOW WHITE LEAVES” EXTRACT

Mathew George*, Lincy Joseph and Kavitha A. K.

ABSTRACT

The aim of the present study was to evaluate the Anti- hyperlipidimic activity of Bougainvillea glabra snow white leaves extract. Bougainvillea glabra snow white is cultivated variety of Bougainvillea glabrachoicy which have white bracts with greenish veins. It is an ornamental flowering plant from the genus of Bougainvillea. Family Nyctaginaceae and a native of Brazil. Free radicle reactions of plant have been implicated in the pathology of atherosclerosis. Anti-hyperlipidemic activity was evaluated by triton 100x and carbontetrachloride induced hyperlipidemia model by using hydroalcoholic extract. This extract (50:50) at different doses, was shown significant(p<0.05) anti-hyperlipidimic activity in both triton 100x and carbontetrachloride induced hyperlipidemia in rats by considering cholesterol, triglycerides, HDL, LDL and VLDL. The histopathological analysis of rats liver was shown that hydroalcoholic extract (50:50) was reduced the excessive deposition of fat in the liver cell and also reduced the mobilization of fats from adipose tissue on the peripheral livert cells and increase the mobilization of free fatty acids from the peripheral depots. The findings of the study suggested that hydroalcoholic extract (50:50) Bougainvillae snow white leaves extract was shown strong Anti- hyperlipidimic activity.

Keywords: Antihyperlipidemic activity, Bougainvillae glabra ‘snow white’, Hydroalcoholic extract, Carbontetrachloride.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process)