EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , 

 ISSN 2394- 3211

Impact Factor: 4.161

 ICV - 79.57

Abstract

AN IN-VITRO STUDY TO TEST ANTIMICROBIAL EFFECTS OF COMMIPHORA MYRRHA IN COMPARISON TO BIOCIDES

Ghada Alotaibi, Dr. Uma M. Irfan* and Dr. Sarah Ali

ABSTRACT

Introduction: Commiphora myrrha (C. myrrha) belongs to the family Burseraceae. Myrrha extract is produced from the oleo-resin gum obtained from the bark of Commiphora molmol, a variable species found in Arabia and Africa. It has been commonly used for treatments of inflammations, as an antipyretic, anti-septic, for infections and ulcers. The aim of this study was to investigate the antimicrobial effects of C. myrrha in comparison to known biocides. Method: C. myrrha resin gum purchased from local markets in Qassim, Saudi Arabia, was washed in clean water to remove debris and dust, then dried in shade and ground to make Myrrha powder. The aqueous and ethanol extracts of C. myrrha powder was evaluated for antibacterial and antifungal activity using the agar disc diffusion and well diffusion methods; against two gram positive, one gram negative and one fungal organism. The diameter of the inhibition zones was measured in millimeters and compared with the antimicrobial activity of known biocides. Results: The 10% ethanol extract of C. myrrha exhibited maximum inhibition with 11.3 mm for Staphylococcus aureus and was comparable to the inhibition zones found with biocides such as Amikacin, Tetracycline, and Amoxicillin. As the serial concentration of the extract increased the inhibition zone increased for S. aureus. However, C. myrrha extracts did not have inhibitory effects on Streptococcus species, E. coli, and Candida albicans. Conclusion: Commiphora myrrha ethanol and aqueous extracts have demonstrated a species-specific antibacterial effect, particularly on Staphylococcus aureus as compared to antibiotics such as Amikacin, Amoxicillin and Tetracycline.

Keywords: Commiphora Myrrha, Antimicrobial Activity, Biocides.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process)