FAST DISSOLVING TABLETS: A NOVEL DRUG DELIVERY SYSTEM

Shehla Khan*, Sadhana Shahi, Santosh Borde and Saliya Shaikh

ABSTRACT

In today’s era, many novel drug delivery approaches have been developed which are aimed at both to increase the performance of the dosage form as well as patient compliance. A fast dissolving tablet is one such novel drug delivery system. FDT dissolves or disintegrates in the oral cavity within seconds without intake of water, has drawn a great attention. Fast dissolving tablet is the safest, most convenient and economical having highest patient compliance especially for geriatric, pediatric, bedridden patients, patients who have swallowing difficulties (dysphagia) and for patients who are busy, travelling or have no access to water. The main advantage of FDT is its quick disintegration in the oral cavity without the aid of water or chewing. It has provided new area of research and development for both industries and academics. This article reviews the importance and unique concept of the fast dissolving tablets with an overview of oral mucosa for drug delivery through it. It also reviews the diverse superdisintegrants used along with different technologies (patented and non patented) employed for the fabrication of fast dissolving tablets, their pros and cons, and characteristics.

Keywords: Fast Dissolving Tablet, Mouth Dissolving Tablet, Fast Disintegrating Tablet, Techniques.