EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

STUDY OF SERUM LIPID PROFILE AND LIPOPROTEIN (a) IN CHRONIC KIDNEY DISEASE

Sudeshna Sil* and Kshounish Sankar Ray

ABSTRACT

Introduction: Chronic Kidney Disease (CKD) is a progressive loss of renal function and decline in Glomerular filtration rate . The disturbances in lipid and lipoprotein metabolism in these patients is one of the major risk factor of cardiovascular diseases. Cardiovascular diseases are the leading causes of morbidity and mortality in these patients. Lipoprotein(a) is an important atherogenic factor in the pathogenesis of cardiovascular diseases. Aim: To study the alteration of lipid profile and lipoprotein(a) in Chronic Kidney Disease patients not on dialysis. Methodology: Case control study involving 30 patients of CKD not on hemodialysis/peritoneal dialysis were taken as cases and 30 age and sex matched healthy persons were taken as controls. The cases were taken from K.P.C Medical College, Kolkata. Renal Function Test (Urea and Creatinine), Lipid profile and Lipoprotein(a) were estimated and the cardiovascular risk ratios were calculated and statistically analysed. Results and Conclusion: Serum Urea and Creatinine were significantly increased in cases compared to controls. Triglycerides(TGL), VLDL-C and Lipoprotein(a) were significantly increased and HDL-C was significantly decreased in cases as compared to the control group. The risk ratios: Total Cholesterol(TC)/HDL-C, TGL/HDL-C were significantly increased in cases as compared to the control group.

Keywords: Chronic Kidney Disease, Lipoprotein(a), Hemodialysis, Cardiovascular diseases, Lipid Profile.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia