EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , 

 ISSN 2394- 3211

Impact Factor: 4.161

 ICV - 79.57

Abstract

EVALUATION OF THE CORRELATION OF GLYCOSYLATED HAEMOGLOBIN WITH CENTRAL CORNEAL THICKNESS AND INTRAOCULAR PRESSURE IN TYPE 2 DIABETES PATIENTS

Dr. Neha Chowdhary and Dr. Gian Chand Rajput*

ABSTRACT

Purpose: To evaluate the correlation of glycosylated haemoglobin (HbA1c) with central corneal thickness (CCT) and intraocular pressure (IOP) in type 2 Diabetes Mellitus (DM) patients. METHODS: Values were obtained from 85 healthy control subjects (Group 1) and 85 subjects with type 2 DM (Group 2) with similar age and sex. Cases were further divided into two groups: Group 2A, diabetes patients with HbA1c <7%; and Group 2B, diabetes patients with HbA1c ≥7%. IOP measurements were obtained using Non Contact Tonometer (NCT). Ultrasound Pachymetry was used to measure CCT and corneal-compensated intraocular pressure (IOPcc). Results: There was statistically significant difference between Groups 1 and 2 in terms of CCT (p=0.003), IOP (p=0.000) and IOPcc (p=0.018). CCT, IOP, IOPcc were statistically significant between Group 1 and 2B (p=0.002, p=0.000, p=0.037) but not between other groups. Conclusion: Type 2 DM subjects were found to have raised CCT, IOP and IOPcc as compared to controls; of which subjects with HbA1c ≥ 7%(Group 2B) were maximally affected which indicates a positive correlation of HbA1c with CCT and IOP.

Keywords: Type 2 Diabetes Mellitus, HbA1c, Central Corneal Thickness, Intraocular Pressure, Corneal-Compensated Intraocular Pressure.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process)