EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

OXIDATIVE STRESS AND SOME INFLAMMATORY BIOMARKERS IN PATIENTS WITH CORONARY HEART DISEASE

Feryal Hashim Rada*

ABSTRACT

Myeloperoxidase is a marker of oxidative stress and is released after neutrophils Energizing. It has potent pro-oxidative and proinflammatory properties. This study was objectives to investigate the impact of myeloperoxidase and some inflammatory biomarkers on the incidence of coronary heart disease. The study was done on 50 patients (30 males and 20 females), aged 55 years ±8 with acute coronary heart disease and 40 healthy subjects (22 males and 18 females), aged 45 years±5 recruited from Ibn Albitar Center for Cardiac Surgery. Lipid profile, myeloperoxidase, many inflammatory biomarkers and cardiac troponin I levels were measured and studied. The results of this study showed that the total cholesterol to HDL cholesterol ratio, inflammatory biomarkers like high sensitive C-reactive protein, interleukin -6 and myeloperoxidase were substantially higher in cases than in non-cases subjects. As well the mean level of cardiac troponin I was higher in patients with acute coronary disease than in control subjects. Conversely, the concentrations of adiponectin were insignificantly altered in cases as compared with control subjects. On conclusion, a combination of myeloperoxidase, cardiac troponin I and inflammatory markers allowed the recognitions of a greater proportion of patients at risk for coronary cardiac events than the use of cardiac troponin I alone.

Keywords: Myeloperoxidase, cardiac troponin I, inflammatory markers and acute coronary disease.


[Full Text Article]

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  • EJPMR SEPTEMBER ISSUE PUBLISHED

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)