EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

OXIDATIVE STRESS ASSESSMENT IN PATIENTS WITH DIABETIC NEPHROPATHY

Feryal Hashim Rada*

ABSTRACT

It is well known that diabetes mellitus is one of the diseases that is associated with oxidative stress and antioxidant mechanism. This study was done to measure and analyze the serum levels of total oxidant and total antioxidant parameters in patients with diabetic nephropathy. A study was done on 45 patients (25 males and 20 females), aged (50 years ±8) with diabetic nephropathy disease and 50 healthy subjects (28 males and 22 females), aged (48 years± 5). Blood level of hemoglobin A1C percent as well serum levels of reactive oxygen metabolites and total antioxidant status were measured and studied. The statistical results for patients with diabetic nephropathy offered high momentous increase (P˂0.001) in blood level of hemoglobin A1C percent as well in serum level of reactive oxygen metabolites when compared with control healthy subjects. Conversely, in contrast to control subjects, the patients with diabetic nephropathy revealed high considerable decrease (P˂0.001) in serum level of total antioxidant status. On Inferences, these observation on patients with diabetic nephropathy, demonstrated the degree of imbalance between oxidative and ant oxidative statuses that may be related to clinical events and complication accompanied diabetic nephropathy.

Keywords: Diabetic nephropathy, reactive oxygen metabolites, Total antioxidant status.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process)