An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57



Rayed H. Khalil*, Amany M. Diab, Medhat S. Shakweer, Hanan A. Ghetas and Khallaf M.


Background: Because of the potential antioxidant, anti-inflammatory, and immune-modulating properties of Spirulina platensis, there is an increased interest in its potential role in the prevention and control of sulfur toxicity in sea bass Dicentrarchus labrax. Objective: This study investigated the effects of sodium sulphate on sea bass (Dicentrarchus labrax) and protection effect of Spirulina platensis. Material and methods: A total of 260 sea bass exposed to 1/10 dose of sodium sulphate 96hr-LC50 (5.8 mg/L) and study the changes in antioxidant enzyme activities of serum. In addition to, study the amelioration of sodium sulphate toxicity by addition of S. platensis to the ration of exposed fish by the rate of 1%. Results: The results showed that the sodium sulphate at dose of 5.8 mg/L the level of SOD; CAT; GPx and TAC activity in the serum of sea bass were decreased. The SOD; CAT; GPx and TAC activity in sodium sulphate exposed group was found lower than the S. platensis supplemented groups. Exposure of sea bass to sodium sulphate for 8th weeks resulted in significant changes in mRNA abundance for a limited subset of the analyzed of hepatic sea bream genes. GSR; SOD and GPXs mRNA levels decrease significantly upon incubation with sodium sulphate, in liver, irrespectively to the length of the treatment, whereas the corresponding levels of sea bass feed with 1% S. platensis were indistinguishable from controls. Discussion and conclusion: S. platensis ameliorated the adverse biochemical effect of sodium sulphate toxicity in sea bass, likely by increasing and improving the antioxidant status.

Keywords: Antioxidant Status, Spirulina Platensis, Sulfur Toxicity, Sea Bass.

[Full Text Article]



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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)