EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

NATURAL CONTRACEPTIVE FOR MALE RATS

*Atef E. Abd El-Baky

ABSTRACT

Many plants have therapeutic actions for some diseases and also, it has adverse effects which can be employed to solve another some problems. This study is aimed mainly on the adverse effect of Citrullus-colocynthis on fertility. Where, fertility control is essential and concerned with national public health. Methods: Thirty male rats were divided into 3 groups, 1st group was kept as control, 2nd and 3rd groups received C-colocynthis extract orally (50 mg, 150 mg /100g B W respectively) day after day for 70 days. Results: There was an increase in hepatic lactate dehydrogenase (LDH), protein thiols (Pr-SHs), reduced glutathione (GSH), glutathione peroxidase (GPx) and superoxid dismutase (SOD). Also, there was an increased in hepatic total protein, albumin, globulin and adenosine triphosphate (ATP) in liver homogenate as compared to the control. The testes weight and the values of deformed head sperm showed an increased. In treated groups the results showed a decreased in sperm number, motility and the number of life sperm in compared with control. Histopathological examination showed some changes in seminiferous tubule with some degenerative changes. Conclusion: C-colocynthis extract had anti-fertility effects on male rats in addition to its antioxidant effects and increasing of ATP and liver protein content.

Keywords: Seeds, Extract, Fertility, Public health, Sperm.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)