EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

LEARNING AND MEMORY ENHANCING ACTIVITY OF A CLASSICAL FORMULATION- ASHVAGANDHADHYA GHRITA, IN SWISS ALBINO MICE

Dr. Vasavdutta Kothari*, Dr. B. J. Patgiri, Dr. Mukesh Nariya and Prof. P. K. Prajapati

ABSTRACT

Ashvagandhadya ghrita is a classical formulation stated in Chakradutt, Vatavyadhi chikitsa. Its ingredients are Ashvagandha kvatha, Ashvagandha kalka, godugdha and goghrita. The individual ingredients have medhya, rasayan, jivaniya etc. properties. Medhya means that which is beneficial for the brain - i.e. beneficial for the intellect, memory and mental abilities. Thus this formulation may have learning and memory enhancing effect and so this was studied by animal experimentation in Swiss albino mice. However, regarding the preparation of this ghirta as per reference, it can be prepared in three days as it contains milk and it can also be prepared in twelve days as it contains roots. So this ghrita was prepared in three days (sample B) and in twelve days (sample C). One sample of this ghrita with Gir cow goghrita and fresh root decoction was also prepared (sample E) as Gir cow goghrita is considered to be superior and as per classical reference Ashvagandha should be used in the fresh state. The result showed that all the samples had learning and memory enhancing activity, the sample E having greatest effect followed by sample B, at a statistically significant level. Sample C did show this activity but it was not at a statistically significant level.

Keywords: Nootropic, Ashvagandhadhya ghrita, learning and memory enhancing activity, Alzheimer?s disease.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)