EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

SYNTHESIS OF RU-NHC COMPLEX FROM CAFFINE AND ITS ACTIVITY AGAINST MALARIAL PARASITES

Karumutchu Sitalu*, B. Hari Babu and A. Lakshmana Rao

ABSTRACT

Present day organometallic science is difficult to envision without flexible N-heterocyclic carbene ligands. Because of their remarkable soundness and auxiliary differing qualities these themes are utilized in incalculable coordination buildings in current days. Specifically, transition metal complexes bearing interchangeable and promptly accessible NHCs have been built up as intense homogeneous catalysts. This field concentrates on particular applications and adjustments. Therefore, the present scientific experts can depend on complex engineered apparatus for the functionalization of carbenes, empowering access to polydentate ligand frameworks with or without hemilabile conduct. With regards to this work, different functionalized carbene ligands were utilized to accomplish or examine particular properties of ruthenium complexes. Tetracarbene ligands are generally unbending structures which empower relatively stable mixes because of their chelating coordination mode. Be that as it may, the basic differences of these themes is frequently restricted because of the low adaptability of the ligand forerunners. Using a non-cyclic, open-chain tetraimidazolium salt, we blended Ru (II) edifices whose geometry can be adjusted relying upon the response conditions. Also, these buildings demonstrated articulated movement in the TH of ketones. The present study focuses on the synthesis of Ru-NHC and its impact on malarial parasites.

Keywords: Carbene compounds, methylated caffeine, XRD, malarial parasite.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia