EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

CORRELATION OF SERUM CHOLECALCIFEROL WITH LEFT VENTRICULAR HYPERTROPHY IN ESSENTIAL HYPERTENSION

Dr. Shahbaz Ali Shah*, Dr. Israr Ahmed Chang, Dr. Kamlesh Kumar, Dr. Ramchandani Santosh and Dr. Umair Arshad Malik

ABSTRACT

Objective: Analysis of serum cholecalciferol in essential hypertension and its correlation with left ventricular hypertrophy (LVH). Study Design: Cross sectional study. Study setting & Duration: Department of Medicine, Jinnah Postgraduate and Medical center , Karachi from September 2015 to March 2016. Subjects and Methods: 100 controls and 100 diagnosed cases of essential hypertension with left ventricular hypertrophy were selected. LVH was estimated by echocardiography. Blood samples were centrifuged at 4000 rpm (10 minutes) to separate sera for biochemical estimation of serum cholecalciferol, serum calcium, serum phosphate and alkaline phosphatase. Statistical analysis was performed on statistical software (SPSS 22.0) and Microsoft excel. Results: Serum cholecalciferol was low in cases 22.84±5.10 ng/dl compared to controls 47.09±7.65 ng/dl (p=0.0001). Mean ± SD interventricular septum and posterior wall thickness was noted as 12.39±1.82 mm in cases. Serum cholecalciferol revealed negative correlation with LVH (r= - 0.774, p=0.0001). Conclusion: Low serum cholecalciferol was found in the essential hypertension with left ventricular hypertrophy.

Keywords: Left ventricular hypertrophy, Essential Hypertension, Cholecalciferol.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia