ANTIMICROBIAL POTENTIAL OF SCHIFF BASE METAL COMPLEXES: AN OVERVIEW

Rajkumar G. Momle, Suresh G. Vedpathak and *Gopal K. Kakade

ABSTRACT

The implication of metal chelation is carried in many important biological processes, where the coordination occurs between different metal ions and a broad range of ligands. Coordination compounds have been considered as characteristic compounds for bio-coordination compounds which controls the process of metabolism. Schiff bases play a vital in the development of chemistry of coordination compounds. As the transition metal complexes contribute a diverse and rich field of research, these complexes received much attention because of their applications in biology, medicine and industry. Schiff bases and its transition metal complexes possess numerous biological properties like antimicrobial, anti-inflammatory, anticancer, analgesic, anticonvulsant, antiviral, anticonvulsant, anthelmintic, anti-HIV, antioxidant, and CNS depressant activities. The present review provides a brief overview on the recent developments on antimicrobial potential of Schiff base transition metal complexes reported in the last few decades.

Keywords: Antibacterial, Antifungal, Antimicrobial, Metal Complexes, Schiff base.