EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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Abstract

PHYTOCHEMICAL SCREENING AND ANTIOXIDANT POTENTIAL OF PAAVU DECOCTION OF KANYAKUMARI DISTRICT, INDIA

R. Mary Suja* and B. Christudhas Williams

ABSTRACT

The main objective of the present investigation is to evaluate the phytochemical constituents and antioxidant potential of Siddha Cancer medicine prescribed by the Traditional Siddha Practitioner of Kanyakumari District, India. Paavu Decoction is an internal form of Breast Cancer medicine prescribed above 18 years was prepared with 21 different plant ingredients. Phytochemical analysis of the Paavu Decoction, aqueous, silver nitrate and ethanol extract revealed the presence of alkaloid, flavanoid, phenol, terpenoid, reducing sugar, tannin, steroid and glycosides except saponin constituents. The unexplored area of hydroxyl radical assay of Paavu Decoction and extracts varied from the minimum scavenging 47.59 ± 0.020 % (25μl) of ethanol extract to the maximum scavenging 81.21 ± 0.025 % (100μl) of L-ascorbic acid, DPPH radical assay varied from the minimum scavenging 44.31 ± 0.025% (25μl) of aqueous extract to the maximum scavenging 83.21 ± 0.011 % (100μl) of Paavu Decoction, nitric oxide radical scavenging varied from the minimum scavenging 37.32 ± 0.030 % (25μl) of aqueous extract to the maximum scavenging 75.26 ± 0.012 % (100μl) of Paavu Decoction, hydrogen per oxide assay varied from the minimum scavenging 42.61 ± 0.010 % (25μl) of aqueous extract to the maximum scavenging 86.31 ± 0.015 % (100μl) of Paavu Decoction and reducing power varied from the minimum scavenging 36.20 ± 0.011 % (25μl) of silver nitrate extract to the maximum scavenging 79.12 ± 0.010 % (100μl) of Paavu Decoction. The antioxidant assay of the Paavu Decoction and extracts indicated promising antioxidant activities in concentration dependent manner. Siddha Cancer drugs highlight the effect of Paavu Decoction as a great potential source to rid Breast Cancer.

Keywords: Paavu Decoction, phytochemical, antioxidant, Kalanchi, Cancer.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia