EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

AN IN-VITRO ASSESSMENT OF THE ANTIMICROBIAL EFFICACY OF FENNEL AND SESAME SEED EXTRACTS AGAINST STREPTOCOCCUS MUTANS

Dr. Jasmin Winnier and Dr. Indu Miriam Varkey*

ABSTRACT

Objectives: Dental Caries is an infectious disease associated with numerous micro-organisms, mainly Streptococcus mutans. In this era of preventive measures, a shift towards natural/herbal products is on the rise. The aim of the study was to evaluate the antimicrobial effect of sesame and fennel seed extract against Streptococcus mutans. Materials and Methods: Aqueous extracts of fennel and sesame seeds were prepared. It was then subjected to microbial assays to determine the Minimum Inhibitory Concentration(MIC), Minimum Bactericidal Concentration (MBC) and Zone of Inhibition against Streptococcus mutans. Chlorhexidine and distilled water were used as a positive and negative control. Results: 100% and 50% concentration of fennel extracts showed inhibition of growth of Streptococcus mutans. 100% of fennel seed extract showed no growth of S mutans on the agar plate, displaying a bactericidal effect. No concentration of sesame extract showed inhibition or bactericidal effect on S mutans. 100% fennel extract showed a Zone of Inhibition (ZOI) of 18 mm. Serial dilutions did not show significant Zone of inhibitions. For sesame extracts, no concentrations showed any ZOI. Conclusion: Fennel extracts show promising results as an antimicrobial agent to be used in clinical conditions. However, sesame seeds used in form of an essential oil mouth rinse as supported by existing literature would yield better results.

Keywords: Fennel, Sesame, Streptococcus mutans, MIC, MBC.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)