SYNTHESIS, CHARACTERIZATION, ANTIOXIDANT, CRYSTALLOGRAPHIC STUDIES OF HETEROCYCLIC SCHIFF BASES AND THEIR BIOLOGICAL EVALUATION
Jitendra N. Borase, R. G. Mahale* and S. S. Rajput
ABSTRACT
The Schiff bases derived from equimolar quantity of ortho substituted aldehyde and primary amine (aromatic amine, Aromatic heterocyclic amine) were prepared via condensation reaction. These Schiff bases were used as ligands to form stable complexes with metal acetate, such as Cu (II), Ni (II), Co (II), Fe (II), Cd (II). The synthesized Schiff bases act as deprotonated tetradentate for the complexation reaction with metal ion. The Schiff bases were characterized by 1H NMR, FTIR SEM, and spectral analysis and furthermore, the entire synthesized product was screening for their biological activity Antioxidant activity.
Keywords: Schiff bases, Heterocyclic amines, Ligands, Antimicrobial Screening, FESEM.
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