EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

ANTIOXIDANT MICRONUTRIENTS AND HEMATOLOGICAL INDICES OF DIABETIC ISCHEMIC STROKE SUBJECTS

Wali U., Yusuf S., Suleiman A. I., Balarabe S. A.*, Bilbis L. S. and Sahabi D. M.

ABSTRACT

Diabetic Ischemic stroke (DIS) is characterized by elevated level of oxidative stress indices, declined antioxidant defenses and hematological impairment. Increased oxidative stress is thought to play a role in the development of DIS and its attendant complications. We investigated serum fasting blood sugar (FBS), malondialdehyde (MDA), Special enzymes such as superoxide dismutase (SOD), glutatuione peroxidase (GPx), Catalase (CAT), Vitamins (A, C, and E), Cu, Cr, Zn, Mn and Se, Rbc counts, Hb, Wbc counts and platelet counts and BP of 37 diabetic Ischemic strokes (DIS) attending Neurology clinic of Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria and the results compared with 42 non-diabetic ischemic stroke (NDIS) subjects. The results suggested significant increased (P<0.05) levels of FBS, MDA and non significant increase (P>0.05) of BP, Wbc counts, Rbc counts and platelet counts and decreased levels of antioxidant enzymes (SOD, GPx and CAT), Vitamins (A, C, and E), minerals (Cu, Cr, Zn, Mn and Se),RBC, counts and Hb in diabetic Ischemic strokes subjects compared with non-diabetic Ischemic stroke subjects. It is concluded that diabetic Ischemic strokes in the study area contribute to depletion of antioxidant defense mechanism and impaired hematological Indices, an indication that the diabetic Ischemic stroke patients are predisposed to increased oxidative onslaught.

Keywords: Antioxidants, Diabetic Ischaemic stroke, oxidative stress micronutrients hematological Indices.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)