STUDY OF NON ALCOHOLIC FATTY LIVER DISEASE & ITS ASSOCIATION WITH METABOLIC SYNDROME IN A TERTIARY CARE CENTRE OF NORTH KARNATAKA

Dr. Ramya D. N. and Dr. Prameela Devi*

ABSTRACT

Background: Non alcoholic fatty liver disease (NAFLD) is Associated with Obesity, Insulin Resistance, and type 2 diabetes. The spectrum of NAFLD ranges from simple fatty liver (hepatic steatosis), with benign prognosis, to a potentially progressive form, non alcoholic steatohepatitis (nash), which may lead to liver fibrosis and cirrhosis, resulting in increased morbidity and mortality. So these patients can be treated earlier and prevented from going into cirrhosis. Objectives: 1. To study the clinical profile of patients of NAFLD with varying degrees of severity as diagnosed by ultrasonography. 2. To study the correlation between the NAFLD and metabolic syndrome along with its individual components. Methodology: this study was done from January 2016 to June 2017.the study was an observational study of patients diagnosed as NAFLD, attending opd and indoor patients of the Department of General Medicine, Hanagal Shri Kumareshwar Hospital attached to Snmc, Bagalkot. NAFLD was diagnosed on the basis of ultrasound assessment of the liver. All patients diagnosed as NAFLD were investigated for metabolic syndrome according to the ncep atp 3 criteria and a relationship between NAFLD and metabolic syndrome was studied. Conclusion: our study reveals higher proportion of all the components of metabolic syndrome in cases of NAFLD. Therefore whenever these parameters are encountered in the clinical setting, patients must be evaluated for the presence of NAFLD by abdominal ultrasonography. The best way to prevent NAFLD is primary prevention; to identify and treat the risk factors.

Keywords: Non alcoholic fatty liver disease, Metabolic syndrome, Tertiary care centre.