EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

ANTIBIOTIC UTILIZATION AND PROPHYLAXIS STUDIES IN PEDIATRIC CARDIAC SURGERY IN A RURAL TERTIARY CARE HOSPITAL IN INDIA

Sohilkhan Riyazkhan Pathan* and Dr. Amit Kumar

ABSTRACT

The present study was conducted to assess the antibiotic utilization and prophylaxis pattern in patients of pediatric cardiac surgery. An observational retrospective study was conducted on 100 pediatric patients who had undergone cardiac surgery in 2017-18. All the data of the patients was received from the medical record department of the Shree Krishna hospital, a tertiary care hospital in rural area, in the state of Gujarat, India. After collecting all the data Descriptive statistic were used to depict profile of study participant and pattern of antibiotic usage. The use of antibiotic prophylaxis in pediatric cardiac surgery in the study group was 100%. In our study we found that 30% patients were started antibiotic before the day of surgery. Out of these patients 30% patients did not need antibiotics as per the institute protocol. Out of 100 patients 87% patients got first line drug as hospitals policy for prophylaxis (cefoperazone and sulbactam + Amikacin), 9% patients got drug piperacillin/tazobactam + Amikacin as they were septic. On base of clinical record and pre-operative investigations 22% patients were given these drugs irrationally. Another 4% patients got piperacillin/tazobactam + teicoplanin. In the last group one had received the higher antibiotics irrationally. Only 27% patients have had an appropriate duration of prophylaxis use. On further evaluation it was found that 40% patients received prophylaxis for more than 48 hours inappropriately. It implies that prolonged use of antibiotics was highly prevalent in our study group. Of the 100 patients, 45 patients were prescribed antibiotics at hospital discharge, again a high number. Out of these 45 patients, 73% patients had given Antibiotics rationally and 27% patients had given antibiotics irrationally. This study gives an important insight of antibiotics misuse in Pediatric cardiac surgical patients and more stringent measures are required to limit & curtail excessive use of antibiotics.

Keywords: Antibiotic Prophylaxis, Pediatric Cardiac Surgery.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)