EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

SUSCEPTIBILITY OF SALMONELLA SPECIES ISOLATED FROM PATIENTS’ STOOL TO COMMONLY USED ANTIBIOTICS

Oguamanam Okezie Enwere* and Kelechi Ihechinyerem Osuagwu

ABSTRACT

Background: Salmonella infection among humans is an important public health challenge. While commonly available antibiotics are regularly used for its treatment, a changing antibiotics susceptibility pattern has been observed over the years. We assessed antibiotic susceptibility to salmonella isolated from patients’ stool. Methodology: Patients had a stool sample collected on clinical assessment of typhoid fever. Stools were then tested for presence of salmonella species in addition to other pathogenic parasites. Isolated cases of salmonella species was then subjected to antibiotic sensitivity using the disc diffusion method. Results: A total number of 105 samples were analyzed and 60 (57.1%) were positive for salmonella species. Salmonella was least resistant to streptomycin (18.3%). The fluoroquinolones, ofloxacin and ciprofloxacin had 33.3% and 35% resistance respectively. Choramphenicol also had 35% resistance, while pefloxacin had the most resistance of the fluoroquinolones at 41.7%. Nalidixic acid had the highest resistance (76.6%). Conclusion: The fluoroquinolones remain the first line drug treatment for salmonella infection. However, we observed a rising level of resistance level compared to previous years. Streptomycin had the least resistance but available only as injection.

Keywords: susceptibility, salmonella, typhi, antibiotics, patients’ stool, common.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)