DRUG-DRUG INTERACTIONS OF PANTOPRAZOLE: AN UPDATED REVIEW
Ramam Sripada, S. V. Suresh Kumar*, N. Devanna and Kandula Ravindra Reddy
ABSTRACT
Proton pump inhibitors (PPIs) are the most commonly used class of drugs in treating the gastric acid related disorders. Among them, pantoprazole is the most extensively prescribed drug in the clinical scenario. When compared to H2 receptor antagonists, proton pump inhibitors had a high healing rate. In this review we mainly focused in reviewing the drug-drug interactions of pantoprazole. Among all the PPIs, the drug interaction profile of pantoprazole has been well established. When compared to omeprazole and esomaprazole, pantoprazole was associated with lower incidences of drug-drug interactions resulting either from their lower affinity for specific CYP isoenzymes or the involvement of additional elimination processes.
Keywords: Drug-drug interactions, Pantoprazole, Proton pump inhibitors..
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