EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

ASSESSMENT OF AUTONOMIC FUNCTION IN RHEUMATOID ARTHRITIS PATIENTS USING TILT-TABLE TEST IN A TERTIARY CARE TEACHING HOSPITAL

Dr. P. V. Saraswathi* and Dr. Amudhan Arvind 

ABSTRACT

Introduction: Rheumatoid Arthritis (RA) is a chronic inflammatory disorder affecting primarily the peripheral joints. This disorder not only affects the joints but also many systems like the Respiratory, Cardiovascular and the Nervous system particularly autonomic nervous system involvement has been commonly encountered among the RA patients. Aim and Objectives: This study was aimed at investigating the various functions of the autonomic nervous system in RA patients and to explore the possible relation between the autonomic nervous system dysfunction with the patient’s age, gender, and disease duration and sero-positivity status of RA. Materials and methodology: This cross sectional study was conducted in a tertiary care hospital among 207 RA patients attending the Rheumatology clinic. Age matched control group included 106 persons. Two tests were used to assess the autonomic function namely the Tilt table test and Postural BP. Results: Although both parasympathetic and sympathetic divisions are affected in rheumatoid arthritis, parasympathetic division suffers more than the sympathetic division. None of our patients who showed an abnormal blood pressure response to tilting were suffered from the symptoms of orthostatic hypotension. Altered autonomic responses has shown significant positive correlation to female RA patients with longer disease duration and sero-positivity and does not show any relationship to the age of the patients. Conclusion: The early detection and treatment of autonomic neuropathy will not only help to reduce the mortality but also certainly improve the quality of life and reduce the sufferings in RA patients.

Keywords: Rheumatoid arthritis, Autonomic dysfunction, tilt table test, orthostatic hypotension.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)