EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

A PILOT STUDY ON EFFICACY OF METFORMIN AND INSULIN ON NEONATAL OUTCOMES IN GESTATIONAL DIABETES MELLITUS PATIENTS

Anand A. S., Liya Kuriakose, Shabina M., Akhila T. S. and Nithin Manohar R.*

ABSTRACT

Background: Pregnancy is a potentially glucose intolerant condition and in all pregnancies insulin sensitivity decreases as pregnancy advances. This predisposes to development of gestational diabetes mellitus. AIM: Aim of this study is to assess the efficacy of Metformin and insulin on neonatal outcomes in GDM patients. Objective: To study and compare the difference in efficacy of Metformin and insulin on neonatal outcomes. Materials and method: It is a prospective observational study in which the sample size is divided into 2 groups. One receving Metformin and other Insulin. Optimum glycemic control between the two groups are studied along with maternal and neonatal outcomes. Results: Glycemic control of both the groups were 95%.Majority of insulin group(60%) have pre term delivery while majority of metformin group have normal delivery(85%). Neonatl hyperbilirubinemia was higher in insulin group(60%) than in metformin group(35%). Discussion: Through our study, it was found maternal glycemic control and most of the neonatal outcomes (birth weight, APGAR score) were comparable between two groups. Neonatal huperbilirubinemia and gestational age of delivery were having significant difference between two groups. Conclusion: Metformin is found to be as effective as Insulin in the treatment of Gestational Diabetes Mellitus. Compared to Insulin, Metformin is a safer, cheap and convenient first line drug of choice for Gestational Diabetes Mellitus.

Keywords: Gestational Diabetes mellitus (GDM), Metformin, Insulin.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)