EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

STATISTICAL OPTIMIZATION OF HERBAL CREAM CONTAINING WOUND HEALING AND ANTIFUNGAL AGENTS

Bhavana Patil, Dr. Padmanabh Deshpande* and Mangesh Bhalekar

ABSTRACT

Different fungi are always present on surface of the skin. Infection occurs when these organisms enter into body. Fungal infection is a very common ailment of day to day life. Wound refers to a sharp injury which damages the dermis of skin. Microbes i.e. bacteria or fungi are found on wounds. Alkaline wound fluid will promote growth of both bacteria and fungi. The aim of the research is to formulate a cream which treats fungal infection as well as heal wounds which occur due to intense scratching and itching. Conventional therapy shows varied side effects and thus it is need of hour to find an alternative therapy. Herbal therapy is the best option here. Thus, the present study focuses on preparation of methanolic extract and herbal oil and formulating it in a patient friendly formulation i.e. Cream. The cream was formulated and optimized by using 32 factorial design with concentration of stearic acid and tween 80: span 20 as factors and viscosity, spreadability and drug release as responses. The cream with 4% tween 80: span 20 and 2 gram stearic acid was considered as optimized. The optimized cream showed maximum drug release through drug (karanj oil) present in oil phase and cream was found to give good results.

Keywords: Karanjin, Rhein, Antifungal and Wound Healing Activity.


[Full Text Article]

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  • EJPMR JULY ISSUE PUBLISHED

    JULY 2018 Issue has been successfully launched on 1 July 2018

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)