THE COMPARATIVE STUDY OF PRE-OPERATIVE SUBLINGUAL MISOPROSTOL VS CONVENTIONAL INTRAVENOUS OXYTOCIN DURING CAESAREAN DELIVERY
Dr. Sarbeswar Mandal*, Dr. Pradip Kumar Saha, Dr. Samik Sanyal, Dr. Neelu Singh, Dr. Disharee Das and
Dr. Binita Kumari
The comparative study of pre-operative sublingual misoprostol vs conventional intravenous oxytocin during Caesarean delivery. Objectives: To evaluate the superiority of sublingual misoprostol to conventional intravenous oxytocin in Caesarean delivery. Methods &Materials: More than one hundred pregnant women were selected among those planned for Caesarean delivery for varied indications. They were assessed according to study criteria and randomised into two groups- Group A (cases, n=50)(treated with 600 μg sublingual misoprostol) and group B (n=50) (treated with conventional intravenous oxytocin -20 IU in 1litre iv fluid @ 60 drops / min) Results: The primary outcomes of each group (Blood loss, transfusion required, chest discomfort, hypotension and admission to ICCU / RCU, death), secondary outcome included short term for women (operation time, oral intake time, mobilisation time, pyrexia, loosemotion, pain, wound healing, satisfaction), short term for baby (delivery time, birth trauma, meconium staining, Apgar score, NICU admission, hospital stay, re-admission, costs) are analysed. Conclusion: As compared to conventional oxytocin, misoprostol can be considered as a better alternative uterotonic drug during Caesarean delivery.
Keywords: Sub-lingual misoprostal, conventional oxytocin, caesarean delivery, uterotonic drug, PPH.
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