EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

RATIONALITY OF FIXED DRUG DOSE COMBINATION – A PROSPECTIVE VIEW IN A TERTIARY CARE HOSPITAL

Neethu J.*, Dr. Babitha M., Soumya R. V., Nithin Manohar R. V., Jisha Vijayan and Sruthy S. A.

ABSTRACT

Cardiovascular morbidity and mortality can be markedly reduced by achieving clinical blood pressure (BP) goals. Fixed dose combination helps to attain the BP goal earlier than would be the case with monotherapy. The main aim of the present study was to assess the prescribing pattern of fixed dose combination (FDC) of antihypertensive drugs. A prospective observational study was conducted in the cardiology department of multispeciality tertiary care hospital for a period of six months. All hypertensive patients prescribed with anti-hypertensive FDCs were randomly selected and their outpatient records were monitored and documented in a specially designed proforma and the data was then suitably analyzed. During the study period, 150 patients met the selection criteria, a total of 26 different anti-hypertensive FDCs were found. Most of the patients on FDCs were in an age group of 60-69 years with an almost equal distribution among both genders. Only 10% of patients presented with hypertension alone. Most of the patients had other concomitant illnesses (heart diseases, followed by dyslipidemia and diabetes mellitus). Most commonly used combination was the RAAS inhibitor (ACEI/ARBS) with diuretic combination (32.6%), followed by RAAS inhibitor with calcium channel blocker (28%). Only one triple drug combination of olmesartan/amlodipine/hydrochlorothiazide was prescribed, which was also most commonly prescribed. The present study emphasizes the need to formulate and implement appropriate prescribing guidelines for FDCs based on local prescribing, and to conduct further studies to analyse and improve the prescribing patterns and promote rational drug use.

Keywords: Antihypertensive-blood pressure-fixed dose combination-hypertension-prescribing pattern.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 October 2018 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

  • EJPMR OCTOBER ISSUE PUBLISHED

    OCTOBER 2018 Issue has been successfully launched on 1 October 2018

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from 4.161 to 4.897 due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)