EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

NEW COLORIMETRIC METHOD DEVELOPMENT AND VALIDATION OF BENZOCAINE BY VISIBLE SPECTROSCOPY

P. Salomi*, S. Arshiya Banu, B. Gowthami, R. Spandana, S. Sivaiah, M. Rajesh Kumar

ABSTRACT

Background & objectives: Benzocaine is a local anesthetic used to relieve pain caused by conditions like mouth ulcers or sores. The present study has been undertaken in order to develop new simple, rapid efficient and reproducible method for the analysis of Benzocaine by using NED as a coloring reagent. Methods: With the help of NED N-(1-Naphthyl) ethylenediamine reagent a new colorimetric method was developed and the color intensity of the resulting solution is measured by using Visible spectroscopy. Results: The proposed U.V. spectrophotometric method was validated by evaluation of validation parameters. The proposed colorimetric methods give good reproductive results for the estimation of Benzocaine. This is very simple, rapid and nowhere involves complicate sample preparation. Conclusion: It is simple and rapid, selective, precise. Hence, suitable for application in routine analysis of pharmaceutical preparation.

Keywords: Benzocaine, NED, Colorimetry, Validation.


[Full Text Article]

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  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 December 2018 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)